GSoC Gupta Lab

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DNA origami is an interdisciplinary area where DNA can be used as a building block for making useful structures at nano scale. DNA pen is an open source software based on the recent work of Peng Yin and his group [1] which can be used (using free hand and digital molecular canvas) to draw an object at nanoscale. Software generates error free DNA sequences which can be used in the wet lab to create the object at the nano scale. Using DNA pen we have drawn several objects including the map of India and sanskrit letter "Om" from free hand molecular canvas and digital letter DNA using digitized molecular canvas.

Software Homepage

(Click the logo)

DNA computing, Molecular programming, DNA nano structures, DNA nanotechnology.

(Student without prerequisites can seek the knowledge in project understanding phase.)

Java.

1. Wei, B., Dai, M., & Yin, P. (2012). Complex shapes self-assembled from single-stranded DNA tiles. Nature, 485(7400), 623-626.
2. Arnav Goyal, Dixita Limbachiya, Shikhar Kumar Gupta, Foram Joshi, Sushant Pritmani, Akshita Sahai and Manish K. Gupta, DNA Pen: A Tool for Drawing on a Molecular Canvas, DNA 19 Conference 2013, Arizona, USA, 2013. (poster) arXiv:1306.0369 [cs.ET].

Dixita Limbachiya

1. Shikhar Gupta (Master student in Molecular Bioengineering in the BIOTEC department of Technische Universitat Dresden, Germany)
2. Foram Joshi (Master student in Nanobiophysics in the BIOTEC department of Technische Universitat Dresden, Germany)